Why Progesterone Is Both Good and Bad for Mood (and How to Treat PMDD)

Mood effects of progesterone.

Progesterone is usually soothing to mood but can sometimes cause anxiety.

A negative mood reaction to changing levels of progesterone is called neurosteroid change sensitivity or premenstrual dysphoric disorder (PMDD) and affects about one in twenty women.

Also, see Top 6 natural treatments for premenstrual mood symptoms.

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Natural Treatment of Menstrual Migraines

menstrual migraines

According to a Lancet review paper, menstrual migraines are more severe than migraines at other times of the cycle.

Possible drivers of menstrual migraines include estrogen withdrawal at the end of the cycle, plus an estrogen-dependent release of prostaglandins and histamine. Body-identical progesterone may help to shelter the brain from estrogen withdrawal and reduce the frequency and intensity of menstrual migraines.

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Perimenopause Is Second Puberty and Is Temporary

Perimenopause, or “second puberty,” is the two to ten years before the final period. It’s different from menopause (or post-menopause), which is the life phase that begins one year after the final period. Symptoms can occur during perimenopause and are temporary.

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The Crucial Difference Between Progesterone and Progestins

progesterone versus progestinProgestins such as drospirenone, levonorgestrel, or medroxyprogesterone are not progesterone.

That’s because progesterone is not a generic term like estrogen. Instead, progesterone refers only to the hormone made by the corpus luteum or taken as oral micronized progesterone.

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