Why Progesterone Is Both Good and Bad for Mood (and How to Treat PMDD)

Mood effects of progesterone.Progesterone is usually calming but can produce a paradoxical anxiety response in some women. It’s called premenstrual dysphoric disorder (PMDD) or neurosteroid change sensitivity and affects about one in twenty women.

It happens because progesterone interacts with GABA receptors in the brain and normally has a calming effect. The same natural level of progesterone can have a stimulating effect in women with PMDD due to a problem with the GABA receptors.

Roadmap to Progesterone

How to make more progesterone.Progesterone is beneficial because it lightens periods. It also reduces inflammation, regulates immune function, and supports healthy thyroid, brain, bones, and breasts.

Do you make enough progesterone? Are you sure? The only way to make progesterone is with ovulation and a healthy luteal phase.