Rescue Prescription for Perimenopause and Menopause

Natural treatment for menopause and perimenopause.

Perimenopause is the two to twelve years before menopause. It can cause heavy periods, mood swings, insomnia, and night sweats.

Menopause (also called post-menopause) is the life phase that begins one year after the last period. The first couple of years can cause hot flashes, weight gain, and insomnia.

Perimenopausal and menopausal symptoms can be relieved by natural treatments such as magnesium, taurine, progesterone, and transdermal estrogen.

Step 1. Magnesium plus taurine

Magnesium boosts GABA, the brain’s main calming or inhibitory neurotransmitter. Together with the calming amino acid taurine, magnesium can improve sleep, mood, and hot flashes. I recommend 300 mg of magnesium plus 3000 mg of taurine.

A 2017 paper, “Magnesium in the gynecological practice: a literature review,” found that magnesium is an effective treatment for the symptoms of menopause and perimenopause and works by “normalizing the action of hormones (mainly progesterone) on the central nervous system.”

👉🏽Tip: For additional relief, consider adding 50 mg of vitamin B6, which is another great way to boost GABA. But be careful with the dose long-term.

Magnesium could be as much treatment as you need for mood, sleep, and hot flashes. Try it for a few weeks, and then, if you’re still suffering, stay on magnesium but look at adding the next step, progesterone.

Step 2. Progesterone or Prometrium for perimenopause

Natural progesterone or micronized progesterone is entirely different from the progestins used in birth control or conventional hormone replacement (HRT). It’s not a drug. It’s the beneficial hormone you used to make in your twenties and thirties.

Progesterone for perimenopause.

Progesterone has many benefits.

 👉🏽 Tip: Consider Prometrium or Utrogestan for perimenopause symptoms.

Magnesium + taurine + progesterone could be enough to relieve symptoms. Try that combination for a few weeks, and then if you still have symptoms, talk to your doctor about adding estrogen.

Step 3. Estrogen therapy

Estrogen is a lot safer than you’ve been led to believe and can be incredibly helpful for sleep, mood, and hot flashes. Most of the cancer risk from conventional hormone replacement was from the synthetic progestin, not estrogen.

If you do decide to add estrogen, choose one that is:

  • Low-dose such as Vagifem (10 mcg estradiol) or Estradot 25 or 50 (25 or 50 mcg estradiol).
  • Body-identical, which means it is identical to human estradiol or estrogen. Fortunately, most (not all) modern conventional estrogen products are body-identical. That includes brands like Vagifem, Estradot, and Sandrena gel. If you’re not certain if your estrogen prescription is body-identical or not, ask me in the comments or consult the table in Hormone Repair Manual.
  • Transdermal, which means you absorb estrogen through your skin from a cream, gel, or patch. It’s better and safer when taken this way.

You can take progesterone without estrogen. But if you take estrogen, you should take progesterone because it has many benefits for sleep, mood, and breasts. That’s true even if you don’t have a uterus. 

For more information, see my perimenopause book Hormone Repair Manual.

Dr Lara Briden
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