Cyclic Progesterone Therapy for PCOS

Progesterone has beneficial anti-androgen properties and can help to promote ovulation. That makes progesterone potentially therapeutic for polycystic ovary syndrome, as described in my recent paper The central role of ovulatory disturbances in the etiology of androgenic polycystic ovary syndrome (PCOS)—Evidence for treatment with cyclic progesterone.

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Ovulation Is the Main Event of the Menstrual Cycle

Anovulatory cycles and pill bleeds.A menstrual cycle is, by definition, an ovulatory cycle in which ovulation is the main event and progesterone is made.

Any other kind of bleed is either an anovulatory bleed or a pill-bleed — neither of which are real menstrual cycles. Ovulatory cycles are the only way to make progesterone which is important for general health, not just for making a baby.  

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Roadmap to Progesterone

how to make progesterone

Progesterone is beneficial because it lightens periods. It also reduces inflammation, regulates immune function, and supports healthy thyroid, brain, bones, and breasts.

Do you make enough progesterone? Are you sure?

The only way to make progesterone is with ovulation and a healthy luteal phase.

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Natural Treatment of Menstrual Migraines

menstrual migraines

According to a new Lancet review paper, menstrual migraines are more severe than migraines at other times of the cycle.

The authors of the paper explain that menstrual migraines are caused by estrogen withdrawal at the end of the cycle together with an estrogen-dependent release of prostaglandins and histamine. They propose progesterone as a possible prevention strategy.

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