Why Progesterone Is Both Good and Bad for Mood (and How to Treat PMDD)

Mood effects of progesterone.Progesterone is usually calming but can produce a paradoxical anxiety response in some women. It’s called premenstrual dysphoric disorder (PMDD) or neurosteroid change sensitivity and affects about one in twenty women.

It happens because progesterone interacts with GABA receptors in the brain and normally has a calming effect. The same natural level of progesterone can have a stimulating effect in women with PMDD due to a problem with the GABA receptors.

Read moreWhy Progesterone Is Both Good and Bad for Mood (and How to Treat PMDD)

How to Survive the Great Progesterone Crash of Perimenopause

perimenopause and stressIn your forties, you may find you don’t cope as well with stress. It happens because losing progesterone during perimenopause can destabilize the HPA (adrenal) axis or stress response system.

This recalibration of the nervous system is why perimenopause is associated with an increased risk of anxiety, depression, and insomnia.

Read moreHow to Survive the Great Progesterone Crash of Perimenopause

Ovulation Is the Main Event of the Menstrual Cycle

Anovulatory cycles and pill bleeds.A menstrual cycle is, by definition, an ovulatory cycle in which ovulation is the main event and progesterone is made.

Any other kind of bleed is either the breakthrough bleed of an anovulatory cycle or a pill-bleed, which are not real menstrual cycles. 

An ovulatory menstrual cycle consists of a follicular phase and a luteal phase.

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How to Lower Estrogen

too much estrogenToo much estrogen can cause heavy periods, breast pain, fibroids, and premenstrual irritability. It can also suppress thyroid function and increase the risk of breast cancer.

What natural treatment works to lower estrogen? To understand that, you need to think about the types of estrogen and why they’re high.

Read moreHow to Lower Estrogen

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