How Science Got It Wrong About Progesterone

Progesterone is important for women's health.

Progesterone is important for women’s health. Yet for decades, it has been ignored or wrongly blamed for side effects it doesn’t cause. How did that happen?

A missed opportunity

Progesterone was discovered shortly after estrogen, missing the chance to be included in the simplified narrative of “testosterone for men and estrogen for women.” To complicate things further, progesterone couldn’t initially be made into an oral medication, so it was sidelined in favor of synthetic progestins.

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How Too Much Testosterone Can Cause Weight Gain in Women

Testosterone causes weight gain in women.

In women, too much testosterone can promote insulin resistance and visceral fat.

That’s why androgen excess is the primary driver of weight gain with polycystic ovary syndrome (PCOS), some types of birth control, and perimenopause.

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What Estrogen Does in Your 40s (and How Progesterone Can Help)

Estrogen rollercoaster of perimenopause

Night sweats, mood swings, and crazy heavy periods. Is this menopause already? And you’re only 42? No, menopause could still be a decade away. This is perimenopause or second puberty, which is the decade or so before your final period.

Perimenopause is different from menopause (or post-menopause), which is the life phase that begins one year after your final period.

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