Why Progesterone Is Both Good and Bad for Mood (and How to Treat PMDD)

mood effects of progesteroneProgesterone calms the brain and promotes sleep. At the same time, progesterone seem to play a role in the mood symptoms of premenstrual dysphoric disorder (PMDD).

How can both things be true? The short answer is that progesterone is usually good for mood but can sometimes be bad.

Keep reading for the longer answer about progesterone and mood.

Read moreWhy Progesterone Is Both Good and Bad for Mood (and How to Treat PMDD)

The Role of Histamine and Mast Cells in PMS and PMDD

mast cells histamine PMDDHere’s something important about PMS or PMDD (premenstrual dysphoric disorder): At least some of the time it’s caused or worsened by histamine or mast cell activation

Histamine can cause allergy-type symptoms such as hives and nasal congestion. Or it can cause anxiety, headaches, fatigue, brain fog, insomnia, and breast tenderness, the typical symptoms of PMS.

Read moreThe Role of Histamine and Mast Cells in PMS and PMDD

The Curious Link Between Estrogen, Mast Cells, and Histamine

Estrogen, mast cells, and histamine.Headaches. Anxiety. Insomnia. Brain fog. Hives. Nasal congestion. These are just a few of the symptoms of histamine intolerance or mast cell activation syndrome.

Histamine problems are more common in women, and are often worse at ovulation and just before the period. Why? Because that’s when estrogen is high compared to progesterone, and estrogen increases histamine.

Read moreThe Curious Link Between Estrogen, Mast Cells, and Histamine

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